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HRID1614090

反应详情

EQUATION

反应方程式

HRID 1614090 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：Cn1ccc[n+]1CC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)C(=NOC(F)F)c3csc(N)n3)[C@H]2SC1.O.O
HCID178480385

未命名化合物

PRODUCTS

生成物

1
结构：Cl.Cn1ccc[n+]1CC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)C(=NOC(F)F)c3csc(N)n3)[C@H]2SC1
HCID178478920

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

1N-Hydrochloric acid (3.9 ml) was added to a solution of 7β-[2-(2-aminothiazol-4-yl)-2-(difluoromethoxyimino)acetamido]-3-(2-methyl-1-pyrazolio)methyl-3-cephem-4-carboxylate dihydrate (syn isomer) (2 g) in water (50 ml). The resultant aqueous solution was lyophilized to give 7β-[2-(2-aminothiazol-4-yl)-2-(difluoromethoxyimino)acetamido]-3-(2-methyl-1-pyrazolio)methyl-3-cephem-4-carboxylate hydrochloride (syn isomer) (2.1 g).