HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 4-Iodopyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Reactant | 4-Iodopyrazole | HCID 77022 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Iodopyrazole | HCID 77022 | — |
| Product | HCID 22064205 | HCID 22064205 | — |
Reaction Steps
When an equivalent amount of 4-iodopyrazole is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19 using toluene as solvent, 2-(4-iodo-1H-pyrazol-1-yl)ethyl chloride is isolated after column chromatography (4-iodopyrazole, Aldrich, 41%, C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE034201 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-0525b5dad7154f6380a51e8f9589c1c1 |
| Source note | uspto-grants-1993_03 |