Hydrochloric Acid → HCID 2818285, compound

HRID 1614113Notes

Reaction equation

HRID 1614113 reaction equation
[OH-].[Na+].[C:3]([CH2:5][C:6]([O:8]C)=[O:7])#[N:4].[CH2:10]1[O:20][C:19]2[CH:18]=[CH:17][C:14]([CH:15]=O)=[CH:13][C:12]=2[O:11]1.Cl>>[C:3]([C:5](=[CH:15][C:14]1[CH:17]=[CH:18][C:19]2[O:20][CH2:10][O:11][C:12]=2[CH:13]=1)[C:6]([OH:8])=[O:7])#[N:4]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 7747Methyl cyanoacetateHCID 8438PiperonalHCID 14798Sodium Hydroxide

Product 1

HCID 2818285HCID 2818285, compound

Conditions

Temperature
95 °C

Procedure

To an aqueous solution containing 14.20 g of sodium hydroxide and 33.75 g of methyl cyanoacetate, 30.32 g of 3,4-(methylenedioxy)benzaldehyde was added, followed by stirring at 95° C. for 16 hours. After completion of the reaction, an aqueous diluted hydrochloric acid solution was added to obtain a pale yellow solid. The resultant solid was recrystallized from ethanol to obtain a crystal having a melting point of 233° C.

Workup

  1. additionwas added
  2. customAfter completion of the reaction
  3. customto obtain a pale yellow solid
  4. customThe resultant solid was recrystallized from ethanol
  5. customto obtain a crystal

Sources & evidence

ORD record
ord-300ad7b00f1d42efb70457bce1b9d3a8
Source dataset
uspto-grants-1993_03
Patent number
US05196147

Reaction notes

Loading…