Acetic Acid → HCID 10356446, compound

HRID 1614158Notes

Reaction equation

HRID 1614158 reaction equation
[CH2:1]([C:3]1[N:7]2[C:8]3[C:13]([N:14]=[CH:15][C:6]2=[N:5][N:4]=1)=[CH:12][C:11]([Cl:16])=[C:10]([Cl:17])[CH:9]=3)[CH3:2].CC(O)=[O:20].OO>O>[CH2:1]([C:3]1[N:7]2[C:8]3[C:13]([NH:14][C:15](=[O:20])[C:6]2=[N:5][N:4]=1)=[CH:12][C:11]([Cl:16])=[C:10]([Cl:17])[CH:9]=3)[CH3:2]

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 19772996HCID 19772996, compound

Product 1

HCID 10356446HCID 10356446, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

The triazole (3) (1.5 g, 5.64 mmol) was added to 47 ml of HOAc, and then 14 ml 30% H2O2 added. The mixture was warmed 4 hours at 50° C., then cooled to room temperature and poured into H2O. The precipitate was filtered and dried, yielding 1.09 g of 1-ethyl-7,8-dichloro-1,2,4-triazolo[4,3-a]quinoxalin-4(5H)-one (4).

Workup

  1. temperaturecooled to room temperature
  2. filtrationThe precipitate was filtered
  3. customdried

Sources & evidence

ORD record
ord-427b5d099ba946b9868bb8dc702cb790
Source dataset
uspto-grants-1993_03
Patent number
US05196421

Reaction notes

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