Allylamine hydrochloride → 5-Acetylamino-2-allylamino-tetraline-hydrochloride

HRID 1614251노트

반응식

HRID 1614251 반응식
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=O)[CH2:10]2)(=[O:3])[CH3:2].[ClH:16].[CH2:17]([NH2:20])[CH:18]=[CH2:19]>>[ClH:16].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]([NH:20][CH2:17][CH:18]=[CH2:19])[CH2:10]2)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 82291Allylamine hydrochlorideHCID 148364565-Acetylamino-2-tetralone

생성물 1

HCID 197732805-Acetylamino-2-allylamino-tetraline-hydrochloride

실험 절차

Starting from 3.04 g (0.015 mol) of 5-acetylamino-2-tetralone and 4.2 g (0.045 mol) of allylaminehydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 3.30 g (78.4% of theory) and with a melting point of 263° C. which does not change after recrystallisation from methanol/water/ether.

출처 및 근거

ORD 기록
ord-bcbcebbd273e4d2ba19cbe79258b957b
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05196454

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