Dopamine → HCID 19773395, compound

HRID 1614252Notes

Reaction equation

HRID 1614252 reaction equation
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=O)[CH2:10]2)(=[O:3])[CH3:2].[NH2:16][CH2:17][CH2:18][C:19]1C=C[C:23]([OH:24])=[C:21](O)[CH:20]=1.[ClH:27].O1C=CC=C1CCN>>[ClH:27].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]([NH:16][CH2:17][CH2:18][C:19]1[O:24][CH:23]=[CH:21][CH:20]=1)[CH2:10]2)(=[O:3])[CH3:2]

Participants

4

Reactant 3

HCID 681DopamineHCID 130455482-(Furan-2-yl)ethan-1-amine hydrochlorideHCID 148364565-Acetylamino-2-tetralone

Product 1

HCID 19773395HCID 19773395, compound

Procedure

Starting from 0.61 g (0.0031 mol) of 5-acetylamino-2-tetralone and 0.9 g (0.006 mol) of 2 (2-furyl)ethylamine-hydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 0.8 g (77.1% of theory) and with a melting point of 256° C., which increases to 257° C. after recrystallisation from methanol/ether.

Sources & evidence

ORD record
ord-4792ae63847248e18762df49d636f09b
Source dataset
uspto-grants-1993_03
Patent number
US05196454

Reaction notes

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