Cinnamylamine hydrochloride, (E)- → 5-Acetylamino-2-(trans-cinnamylamino)-tetralinehydrochloride

HRID 1614254노트

반응식

HRID 1614254 반응식
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=O)[CH2:10]2)(=[O:3])[CH3:2].[ClH:16].[CH2:17]([NH2:26])/[CH:18]=[CH:19]/[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[ClH:16].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]([NH:26][CH2:17]/[CH:18]=[CH:19]/[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH2:10]2)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 6444486Cinnamylamine hydrochloride, (E)-HCID 148364565-Acetylamino-2-tetralone

생성물 1

HCID 197732815-Acetylamino-2-(trans-cinnamylamino)-tetralinehydrochloride

실험 절차

Starting from 1.02 g (0.005 mol) of 5-acetylamino-2-tetralone and 1.7 g (0.01 mol) of trans-cinnamylamine-hydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 1.1 g (61.6% of theory) and with a melting point of 257° C., which does not change after recrystallisation from methanol/ether.

출처 및 근거

ORD 기록
ord-ce327e0501754cb9bf7e0231974a6b52
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05196454

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