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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1614254Generated: October 26, 2026

Cinnamylamine hydrochloride, (E)- → 5-Acetylamino-2-(trans-cinnamylamino)-tetralinehydrochloride

https://huagongshe.com/reaction/1614254

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCinnamylamine hydrochloride, (E)-HCID 6444486—
Reactant5-Acetylamino-2-tetraloneHCID 14836456—
Product5-Acetylamino-2-(trans-cinnamylamino)-tetralinehydrochlorideHCID 19773281—

Reaction Steps

Starting from 1.02 g (0.005 mol) of 5-acetylamino-2-tetralone and 1.7 g (0.01 mol) of trans-cinnamylamine-hydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 1.1 g (61.6% of theory) and with a melting point of 257° C., which does not change after recrystallisation from methanol/ether.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05196454
Source datasetuspto-grants-1993_03
ORD IDord-ce327e0501754cb9bf7e0231974a6b52
Source noteuspto-grants-1993_03