2-Bromomethylnaphthalene → HCID 19771924, compound
Reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1.[F:13][C:14]1[CH:25]=[CH:24][C:17]([C:18]([CH:20]2[CH2:23][NH:22][CH2:21]2)=[O:19])=[CH:16][CH:15]=1>>[F:13][C:14]1[CH:15]=[CH:16][C:17]([C:18]([CH:20]2[CH2:23][N:22]([CH2:2][C:3]3[CH:12]=[CH:11][C:10]4[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=4)[CH:4]=3)[CH2:21]2)=[O:19])=[CH:24][CH:25]=1Participants
3
Procedure
Following the procedure of Preparation 9, the title compound is prepared from 2-bromomethylnaphthalene and 3-(4-fluorobenzoyl)azetidine.
Workup
- customthe procedure of Preparation 9
Sources & evidence
- ORD record
- ord-44ed4dc684414b4b87f9ccc778ec4f48
- Source dataset
- uspto-grants-1993_03
- Patent number
- US05198449
Reaction notes
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