HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[[(3,4-Difluorophenyl)amino](4-fluorophenyl)methyl]piperidine → 1-[3-[(4-Chlorophenyl)sulfinyl]propyl]-N-(3,4-difluorophenyl)-alpha-(4-fluorophenyl)-4-piperidinemethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[[(3,4-Difluorophenyl)amino](4-fluorophenyl)methyl]piperidine | HCID 19772031 | — |
| Reactant | 1-(p-Chlorophenylsulfinyl)-3-chloropropane | HCID 19772071 | — |
| Product | 1-[3-[(4-Chlorophenyl)sulfinyl]propyl]-N-(3,4-difluorophenyl)-alpha-(4-fluorophenyl)-4-piperidinemethanamine | HCID 19771967 | — |
Reaction Steps
Following the procedure of Example 2, the title compound is prepared from 1-chloro-4-[(3-chloropropyl)sulfinyl]benzene and N-(3,4-difluorophenyl)-α-(4-fluorophenyl)-4-piperidinemethanamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05198449 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-e6ce045b5d9a476c89f5a5a86e9a29c8 |
| Source note | uspto-grants-1993_03 |