Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1614651Generated: October 27, 2026

1-Chloro-4-[(3-chloropropyl)sulfonyl]benzene → 1-[3-[(4-Chlorophenyl)sulfonyl]propyl]-N-(3,4-difluorophenyl)-alpha-(4-fluorophenyl)-4-piperidinemethanamine

https://huagongshe.com/reaction/1614651

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-[(3-chloropropyl)sulfonyl]benzeneHCID 16784262—
Reactant4-[[(3,4-Difluorophenyl)amino](4-fluorophenyl)methyl]piperidineHCID 19772031—
Product1-[3-[(4-Chlorophenyl)sulfonyl]propyl]-N-(3,4-difluorophenyl)-alpha-(4-fluorophenyl)-4-piperidinemethanamineHCID 19772027—

Reaction Steps

Following the procedure of Example 2, the title compound is prepared from 1-chloro-4-[(3-chloropropyl)sulfonyl]benzene and N-(3,4-difluorophenyl)-α-(4-fluorophenyl)-4-piperidinemethanamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05198449
Source datasetuspto-grants-1993_03
ORD IDord-f013fc28722b4f88b720bcc8f93e863a
Source noteuspto-grants-1993_03