1,2-Dimethoxyethane → HCID 67877886, compound

Participants

Reaction Steps

By the use of 1.7 g of 2-[(Z)-2-(3-aminophenyl)ethenyl]-6-[4-(4-methylphenyl)butoxy]methylpyridine obtained in Example 1(2), 1.1 g of anhydrous diethyl succinate, 0.75 g of sodium acetate and 10 ml of dimethoxyethane, the reaction was similarly carried out as Example 1(3). The obtained crystals was recrystallized from 50% an aqueous ethanol to give 0.86 g of 2-[(Z)-2-(3-(3-carboxy-3-ethylvalerylamino)phenyl)ethenyl]-6-[4-(4-methylphenyl)butoxy]methylpyridine, melting at 114°-116° C. as white crystals.

Provenance & Evidence