Benzaldehyde → 1-butyl-6-methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione

HRID 16147Notes

Reaction equation

HRID 16147 reaction equation
[CH2:1]([N:5]1[C:10]2=[N:11][C:12](=[O:17])[N:13]([CH3:16])[C:14](=[O:15])[C:9]2=[N:8][C:7]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20](OC3C=CC=CC=3)[CH:19]=2)=[N:6]1)[CH2:2][CH2:3][CH3:4].C(=O)C1C=CC=CC=1>>[CH2:1]([N:5]1[C:10]2=[N:11][C:12](=[O:17])[N:13]([CH3:16])[C:14](=[O:15])[C:9]2=[N:8][C:7]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[N:6]1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 240BenzaldehydeHCID 117418881-Butyl-6-methyl-3-[3-phenoxyphenyl]-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione

Product 1

HCID 103580971-butyl-6-methyl-3-phenylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione

Procedure

Compound 22 is prepared, as described in 4, by reacting the hydrazine 20 (176 mg, 0.54 mmol) with benzaldehyde (55 μl, 0.54 mmol).

Sources & evidence

ORD record
ord-c3cd86d862734940bab6fbc6eb2356c0
Source dataset
uspto-grants-2010_06
Patent number
US07737144B2

Reaction notes

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