反应详情

Crude ethyl N-(diphenylmethylene)-DL 3,3-diphenylalaninate is added to 2.5 L of 6N hydrochloric acid solution and heated at reflux for 6 hours. The reaction mixture is allowed to cool to room temperature overnight. The product is collected, washed with water (3×), diethyl ether (4×), and dried at 50° C./200 mm Hg. This affords 93.6 g of the title compound as a white crystalline material; mp >210° C. (dec).

1. temperatureheated
2. temperatureat reflux for 6 hours
3. customThe product is collected
4. washwashed with water (3×), diethyl ether (4×)
5. customdried at 50° C./200 mm Hg