HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67996182, compound → HCID 67996049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67996182 | HCID 67996182 | — |
| Reactant | (9-Hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-acetaldehyde | HCID 86668369 | — |
| Product | HCID 67996049 | HCID 67996049 | 77% |
Reaction Steps
The title compound is prepared from (9-hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-acetaldehyde and (S)-1-(4-difluoromethyl-phenyl)-ethylamine following a procedure analogous to that described in Step 3 of Intermediate 2. Yield: 77% of theory; LC (method 8): tR=1.10 min; Mass spectrum (ESI+): m/z=398 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765744B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-9607c5113c4b48cfa70d5743d104cdb9 |
| Source note | uspto-grants-2014_07 |