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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1615152Generated: October 31, 2026

HCID 67996182, compound → HCID 67996049, compound

https://huagongshe.com/reaction/1615152

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67996182HCID 67996182—
Reactant(9-Hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-acetaldehydeHCID 86668369—
ProductHCID 67996049HCID 6799604977%

Reaction Steps

The title compound is prepared from (9-hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-acetaldehyde and (S)-1-(4-difluoromethyl-phenyl)-ethylamine following a procedure analogous to that described in Step 3 of Intermediate 2. Yield: 77% of theory; LC (method 8): tR=1.10 min; Mass spectrum (ESI+): m/z=398 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765744B2
Source datasetuspto-grants-2014_07
ORD IDord-9607c5113c4b48cfa70d5743d104cdb9
Source noteuspto-grants-2014_07