HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68089459, compound → HCID 68089375, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68089459 | HCID 68089459 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 68089375 | HCID 68089375 | 95.2% |
Reaction Steps
tert-Butyl methyl(5-nitro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate (2.2 g, 7.1 mmol) in 2.0 M hydrochloric acid in Et2O (30 mL) was stirred at room temperature for 3 h. The volatiles were removed to give N-methyl-5-nitro-2,3-dihydrobenzo[b][1,4]dioxin-6-amine (1.42 g, 95% yield). ESI MS: m/z 211 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765760B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-711e6106326b452590e0633e62ddcb87 |
| Source note | uspto-grants-2014_07 |