HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 86667820, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 68089388 | HCID 68089388 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86667820 | HCID 86667820 | 96% |
Reaction Steps
To a solution of 3-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)butanoic acid (200 mg, 0.086 mmol) in DCM (15 mL) was added oxalyl chloride (3 mL) and DMF (0.1 mL). The mixture was stirred at room temperature for 2 h. The mixture was then evaporated under reduced pressure to give the product as a brown solid (208 mg, 96% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765760B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-16c51014509141acaa07677d717f2074 |
| Source note | uspto-grants-2014_07 |