Lithium Hydroxide → HCID 68154442, compound

Participants

Reaction Steps

10 mg (0.42 mmol) lithium hydroxide in 800 μl water were added to 105 mg (0.21 mmol) (2S)-tert-butyl-2-(cycloheptylmethyl)-5-(3,5-difluorophenyl)-4-(2-methoxy-2-oxoethyl)-3-oxopiperazine-1-carboxylate in 2 ml THF. After 2 h tetrahydrofuran was distilled off and the aqueous solution was neutralised with hydrochloric acid. The aqueous phase was extracted with ethyl acetate. The ethyl acetate phase was dried and evaporated down.

Provenance & Evidence