Hydrochloric Acid → HCID 68154283, compound

Participants

Reaction Steps

12 mg (0.48 mmol) lithium hydroxide were added to 0.20 g (0.43 mmol) tert-butyl 5-(3,5-difluorophenyl)-4-(2-methoxy-2-oxoethyl)-3-oxo-2-(tetrahydro-2H-pyran-4-yl)piperazine-1-carboxylate (isomer mixture 2.1) in 5 ml THF and 1 ml of water. The mixture was stirred for 2 h at RT, adjusted to pH=7 with 0.1 M hydrochloric acid solution and then evaporated to dryness.

Provenance & Evidence