HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(1H-Indol-4-yl)-1-methyl-4-nitro-1H-indazole → 6-(1H-Indol-4-yl)-1-methyl-1H-indazol-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(1H-Indol-4-yl)-1-methyl-4-nitro-1H-indazole | HCID 58267990 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 6-(1H-Indol-4-yl)-1-methyl-1H-indazol-4-amine | HCID 58268023 | 157% |
Reaction Steps
6-(1H-Indol-4-yl)-1-methyl-4-nitro-1H-indazole (49 mg, 0.17 mmol) was dissolved in ethyl acetate (10 ml) and treated with 10% Pd/C (5 mg) then stirred under hydrogen for 2 h before stirring under nitrogen over the weekend. The reaction was filtered through a Celite cartridge, washing with ethyl acetate, then evaporated to dryness to give the title compound (70 mg) as a grey solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765743B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-a1d29d93a55e4fcc90747150e8e20905 |
| Source note | uspto-grants-2014_07 |