反应详情

6-(1H-Indol-4-yl)-1-methyl-4-nitro-1H-indazole (49 mg, 0.17 mmol) was dissolved in ethyl acetate (10 ml) and treated with 10% Pd/C (5 mg) then stirred under hydrogen for 2 h before stirring under nitrogen over the weekend. The reaction was filtered through a Celite cartridge, washing with ethyl acetate, then evaporated to dryness to give the title compound (70 mg) as a grey solid.

1. stirringbefore stirring under nitrogen over the weekend
2. filtrationThe reaction was filtered through a Celite cartridge
3. washwashing with ethyl acetate
4. customevaporated to dryness