Phenylurea → HCID 944357, compound

HRID 1616130Notes

Reaction equation

HRID 1616130 reaction equation
Br[C:2]1[CH:11]=[C:10]([C:12]([O:14][CH3:15])=[O:13])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=O.[C:16]1([NH:22][C:23]([NH2:25])=[O:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[O:24]=[C:23]1[N:22]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:4](=[O:6])[C:3]2[C:2](=[CH:11][C:10]([C:12]([O:14][CH3:15])=[O:13])=[CH:9][CH:8]=2)[NH:25]1

Participants

3

Reactant 2

HCID 6145PhenylureaHCID 87741Dimethyl 2-bromoterephthalate

Product 1

HCID 944357HCID 944357, compound

Procedure

The title compound was prepared from dimethyl 2-bromoterephthalate (1.50 g, 5.5 mmol) and phenylurea (0.97 g, 7.1 mmol) following the procedure outlined in Example 14, step 1 (1.3 g, 79%). LC-MS: (FA) ES+ 297.

Sources & evidence

ORD record
ord-d9ddd09aeb8b42c5a121ee848f838841
Source dataset
uspto-grants-2014_07
Patent number
US08765773B2

Reaction notes

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