HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Bromopropyl)-4-chlorobenzene → Methyl 2-[3-(4-chlorophenyl)propyl]-1-oxo-1,2-dihydroisoquinoline-7-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Bromopropyl)-4-chlorobenzene | HCID 9881136 | — |
| Reactant | Methyl 1-oxo-1,2-dihydroisoquinoline-7-carboxylate | HCID 60075037 | — |
| Product | Methyl 2-[3-(4-chlorophenyl)propyl]-1-oxo-1,2-dihydroisoquinoline-7-carboxylate | HCID 67282807 | — |
Reaction Steps
The title compound was prepared from 1-(3-bromopropyl)-4-chlorobenzene (0.35 g, 1.48 mmol) and methyl 1-oxo-1,2-dihydroisoquinoline-7-carboxylate (0.20 g, 0.98 mmol) following the procedure outlined in Example 3, step 1 (0.16 g, 44%). LC-MS: (FA) ES+ 356.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765773B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-47d1fd7812df443d8eccdf584b40952b |
| Source note | uspto-grants-2014_07 |