HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzaldehyde → Methyl 2-{2-[(4-chlorobenzyl)(4-methoxyphenyl)amino]ethyl}-1-oxo-1,2-dihydroisoquinoline-7-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzaldehyde | HCID 7726 | — |
| Reactant | Methyl 2-{2-[(4-methoxyphenyl)amino]ethyl}-1-oxo-1,2-dihydroisoquinoline-7-carboxylate | HCID 67282872 | — |
| Product | Methyl 2-{2-[(4-chlorobenzyl)(4-methoxyphenyl)amino]ethyl}-1-oxo-1,2-dihydroisoquinoline-7-carboxylate | HCID 67282892 | — |
Reaction Steps
The title compound was prepared from methyl 2-{2-[(4-methoxyphenyl)amino]ethyl}-1-oxo-1,2-dihydroisoquinoline-7-carboxylate (60 mg, 0.17 mmol) and 4-chlorobenzaldehyde (34 mg, 0.24 mmol) following the procedure outlined in Example 54, step 3 (50 mg, 62%). LC-MS: (FA) ES+ 477.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765773B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-a3ed6c3f86aa4f978c4b64af05052656 |
| Source note | uspto-grants-2014_07 |