HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → Methyl 1-oxo-2-(2-piperidin-1-ylethyl)-1,2-dihydroisoquinoline-7-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Methyl 2-(2-bromoethyl)-1-oxo-1,2-dihydroisoquinoline-7-carboxylate | HCID 67281903 | — |
| Product | Methyl 1-oxo-2-(2-piperidin-1-ylethyl)-1,2-dihydroisoquinoline-7-carboxylate | HCID 67282768 | — |
Reaction Steps
The title compound was prepared from methyl 2-(2-bromoethyl)-1-oxo-1,2-dihydroisoquinoline-7-carboxylate (96 mg, 0.31 mmol) and piperidine (0.31 mL, 3.1 mmol) following the procedure outlined in Example 44, step 2 (80 mg, 82%). LC-MS: (FA) ES+ 315.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765773B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-56d14f495fff4f3d82baa13fd9c4dc37 |
| Source note | uspto-grants-2014_07 |