HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
tert-Butyl 3-(bromomethyl)phenylcarbamate → Methyl 2-{3-[(tert-butoxycarbonyl)amino]benzyl}-1-oxo-1,2-dihydroisoquinoline-7-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | tert-Butyl 3-(bromomethyl)phenylcarbamate | HCID 14523558 | — |
| Edukt | Methyl 1-oxo-1,2-dihydroisoquinoline-7-carboxylate | HCID 60075037 | — |
| Produkt | Methyl 2-{3-[(tert-butoxycarbonyl)amino]benzyl}-1-oxo-1,2-dihydroisoquinoline-7-carboxylate | HCID 67281970 | — |
Reaktionsschritte
The title compound was prepared from tert-butyl[3-(bromomethyl)phenyl]carbamate (0.42 g, 1.48 mmol) and methyl 1-oxo-1,2-dihydroisoquinoline-7-carboxylate (0.20 g, 0.98 mmol) following the procedure outlined in Example 3, step 1 (0.31 g, 77%). LC-MS: (FA) ES+ 409.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08765773B2 |
| Quelldatensatz | uspto-grants-2014_07 |
| ORD ID | ord-b976d0cceef543a4b5134626dce4738c |
| Quellennotiz | uspto-grants-2014_07 |