Benzyl Bromide → 1-(Benzyloxy)-3-bromo-5-fluorobenzene

HRID 1616938Notes

Reaction equation

HRID 1616938 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[C:6]([F:8])[CH:7]=1.[CH2:10](Br)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH2:10]([O:9][C:4]1[CH:5]=[C:6]([F:8])[CH:7]=[C:2]([Br:1])[CH:3]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 219046363-Bromo-5-fluorophenol

Product 1

HCID 112545161-(Benzyloxy)-3-bromo-5-fluorobenzene

Procedure

Prepared as described for 1-bromo-2-fluoro-3-isopropoxy-benzene SM23 using 3-bromo-5-fluorophenol and benzylbromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c0d1e51ec0934ddb9690be3bde25340b
Source dataset
uspto-grants-2014_07
Patent number
US08765779B2

Reaction notes

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