1,3-Dibromo-5,5-dimethylhydantoin → HCID 53307690, compound

HRID 1616984Notes

Reaction equation

HRID 1616984 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:13](=[O:14])[NH:12][NH:11][C:10]2=[O:15])=[CH:5][CH:4]=1)#[CH:2].BrN1C(C)(C)C(=O)N(Br)C1=O>CC#N>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([N:9]2[C:10](=[O:15])[N:11]=[N:12][C:13]2=[O:14])=[CH:7][CH:8]=1)#[CH:2]

Participants

4

Reactant 2

HCID 64791,3-Dibromo-5,5-dimethylhydantoinHCID 53307689HCID 53307689, compound

Product 1

HCID 53307690HCID 53307690, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent2×

Procedure

To a solution of compound 13e (4.43 mg, 0.022 mmol) in CH3CN (44 μL) was added 1,3-dibromo-5,5-dimethylhydantoin (6.29 mg, 0.022 mmol) at room temperature. The resulting solution was stirred at room temperature for 10 minutes. The obtained material was easily degraded at temperature. Therefore, the 0.5 M CH3CN mixture reaction solution was used for next reaction without purification after confirmation of reaction color changing from clear to material specific deep red.

Workup

  1. customwas used for next reaction without purification
  2. customafter confirmation of reaction color

Sources & evidence

ORD record
ord-c9d597c64f8f48049cb2f9e12c16dac9
Source dataset
uspto-grants-2014_07
Patent number
US08765920B2

Reaction notes

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