2,6-Dimethylphenol → 1-(4-Hydroxy-3,5-dimethylphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione

Participants

Role	Name	HCID	Charge
Reactant	2,6-Dimethylphenol	HCID 11335	—
Reactant	1-(4-Hydroxyphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione	HCID 67258169	—
Product	1-(4-Hydroxy-3,5-dimethylphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione	HCID 67258590	—

Reaction Steps

Compound 30 was prepared from 2,6-dimethylphenol in the same manner of compound 27, and was obtained as white solids (61%). 1H NMR (300 MHz, DMSO-d6): δ 11.32 (br s, 1H), 8.42 (s, 1H), 7.53-7.39 (m, 5H), 7.14 (d, J=1.8 Hz, 1H). 13C NMR (75 MHz, DMSO-d6): δ 152.07, 151.38, 129.58, 127.13, 125.61, 121.94, 121.48, 17.43. HRMS: calcd for C16H15N3O3 (MH+) 298.1186. found 298.1184.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08765920B2
Source dataset	uspto-grants-2014_07
ORD ID	ord-198464b6ca1a4f698c0f43cbd4e7422d
Source note	uspto-grants-2014_07