P-Cresol → 1-(2-Hydroxy-5-methylphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione

HRID 1616988Notes

Reaction equation

HRID 1616988 reaction equation
[CH:1]1[C:6]([OH:7])=[CH:5][CH:4]=[C:3]([CH3:8])[CH:2]=1.OC1C=CC([N:16]2[C:20](=[O:21])[N:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[C:18](=[O:28])[NH:17]2)=CC=1>>[OH:7][C:6]1[CH:5]=[CH:4][C:3]([CH3:8])=[CH:2][C:1]=1[N:16]1[C:20](=[O:21])[N:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:18](=[O:28])[NH:17]1

Participants

3

Reactant 2

HCID 2879P-CresolHCID 672581691-(4-Hydroxyphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione

Product 1

HCID 672578141-(2-Hydroxy-5-methylphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione

Procedure

Compound 32 was prepared from p-cresol in the same manner of compound 27, and was obtained as white solids (60%).

Sources & evidence

ORD record
ord-55ba12c355ee401591e22953ef822241
Source dataset
uspto-grants-2014_07
Patent number
US08765920B2

Reaction notes

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