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HRID16171

反应详情

EQUATION

反应方程式

HRID 16171 的结构方程式

REACTANTS

反应物

2
结构：CCOC=O
HCID8025

Ethyl formate

C3H6O2

结构：COCCN[C@@H]1CCCN2c3c(ccc(Cl)c3Cl)Oc3ccccc3[C@H]12
HCID86599878

未命名化合物

PRODUCTS

生成物

1
结构：O=CN[C@@H]1CCCN2c3c(ccc(Cl)c3Cl)Oc3ccccc3[C@H]12
HCID86599879

未命名化合物

收率 30%

PROCEDURE

实验过程

A solution of trans-6,7-dichloro-2,3,4,14b-tetrahydro-N-(2-methoxyethyl)-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepine-1-amine (122 mg, 0.36 mmol) in ethyl formate was stirred overnight at reflux temperature. After removal of the solvent under reduced pressure, the remaining product was purified with preparative LC-MS to give the title compound (40 mg, 30%). Data (m/z)=397 (M+H)+.

WORKUP

后处理

  1. temperatureat reflux temperature
  2. customAfter removal of the solvent under reduced pressure
  3. customthe remaining product was purified with preparative LC-MS