反应详情

The product from example 1 step (v) (0.2 g) was dissolved in THF (10 mL) then methyl 2-(3-formylphenoxy)acetate (0.154 g) was added and stirred at rt overnight. Sodium borohydride (0.0301 mg) was added and stirred for 3 hr. The reaction was quenched with water and extracted with EtOAc, dried and solvent removed under reduced pressure. The residue was purified by RPHPLC to afford the title compound 0.038 g.

1. stirringstirred for 3 hr
2. customThe reaction was quenched with water
3. extractionextracted with EtOAc
4. customdried
5. customsolvent removed under reduced pressure
6. customThe residue was purified by RPHPLC