反应详情

2-Mesitylenesulfonyl chloride (3.65 g) was added to a stirred mixture of the product from step (ii) (5 g), TEA (4.2 ml) and DMAP (0.2 g) in DCM (100 ml) at rt under nitrogen. The mixture was stirred at rt for 4 h then partitioned between DCM and water. The organics were separated, washed with aq NaHCO3 soln, water, dried and evaporated under reduced pressure to afford the subtitle compound, 6.49 g.

1. customthen partitioned between DCM and water
2. customThe organics were separated
3. washwashed with aq NaHCO3 soln
4. dry with materialwater, dried
5. customevaporated under reduced pressure