Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617481Generated: October 25, 2026

2-Fluoro-4-iodo-6-methylpyridine → 1-(2-Fluoro-6-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one

https://huagongshe.com/reaction/1617481

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-iodo-6-methylpyridineHCID 44754752—
ReactantN-Methoxy-N-methyl-3,3-diphenyl-propionamideHCID 54293842—
Product1-(2-Fluoro-6-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-oneHCID 66666361—

Reaction Steps

In analogy to example 55, step 2, from N-methoxy-N-methyl-3,3-diphenyl-propionamide and 2-fluoro-4-iodo-6-picoline was prepared the title compound as an off-white solid, MS (ESI+): m/z=320.1449 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-b459a6e478974dd4b6a3ca5daf32d824
Source noteuspto-grants-2014_07