HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → 1-(2-Fluoro-5-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 1-(2-Fluoro-5-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one | HCID 67015543 | — |
| Product | 1-(2-Fluoro-5-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one oxime | HCID 136359975 | — |
Reaction Steps
In analogy to example 1, step 2, from 1-(2-fluoro-5-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a mixture of E and Z isomers (1.5:1) as a white oil, MS (ESI+): m/z=335.1 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-291c89b832da4fad8e1103c2f333f36f |
| Source note | uspto-grants-2014_07 |