Methanamine, N-methoxy-, hydrochloride (1:1) → 2-(9H-Fluoren-9-yl)-N-methoxy-N-methyl-acetamide

HRID 1617490Notes

Reaction equation

HRID 1617490 reaction equation
[CH:1]1[C:13]2[CH:12]([CH2:14][C:15](O)=[O:16])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.Cl.[CH3:19][NH:20][O:21][CH3:22]>>[CH:5]1[C:13]2[CH:12]([CH2:14][C:15]([N:20]([O:21][CH3:22])[CH3:19])=[O:16])[C:11]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[C:1]=2[CH:2]=[CH:3][CH:4]=1

Participants

3

Reactant 2

HCID 81138Methanamine, N-methoxy-, hydrochloride (1:1)HCID 94852Fluorene-9-acetic acid

Product 1

HCID 866609452-(9H-Fluoren-9-yl)-N-methoxy-N-methyl-acetamide

Procedure

In analogy to example 55, step 1, from fluorene-9-acetic acid (CAS RN: [6284-80-6]) and N,O-dimethylhydroxylamine hydrochloride was prepared the title compound as an off-white oil, MS (ESI+): m/z=268.1 ([M+H]+).

Sources & evidence

ORD record
ord-a7deb74daa8446ff849481a1cf55acff
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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