Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617515Generated: November 1, 2026

3-Chloro-4-(methoxycarbonyl)benzeneboronic acid → 3-Chloro-4'-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/1617515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-(methoxycarbonyl)benzeneboronic acidHCID 23005335—
Reactant3-(4-Bromo-phenyl)-1-(2-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-oneHCID 66668180—
Product3-Chloro-4'-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carboxylic acid methyl esterHCID 66666084—

Reaction Steps

In analogy to example 74, step 6, from 3-(4-bromo-phenyl)-1-(2-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one (example 74, step 5) and (3-chloro-4-methoxycarbonyl)benzeneboronic acid was prepared the title compound as a colorless oil, MS (ESI+): m/z=484.1680 ([M+H]+, 1Cl).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-b908a0ca9f0c4e17b56601c6fc367e4a
Source noteuspto-grants-2014_07