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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617531Generated: November 1, 2026

Hydroxyamine hydrochloride → HCID 136359997, compound

https://huagongshe.com/reaction/1617531

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 67015528HCID 67015528—
ProductHCID 136359997HCID 136359997—

Reaction Steps

In analogy to example example 74, step 7, from 4′-[(S)-3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carboxylic acid ((R)-1-phenyl-ethyl)-amide and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a mixture of E and Z isomers (3.4:1) as a colorless oil, MS (ESI+): m/z=553.702 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-42f05074276c46f292f60f581f082dd7
Source noteuspto-grants-2014_07