HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-4-iodo-6-methylpyridine → 3-(3-Bromo-phenyl)-1-(2-fluoro-6-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-4-iodo-6-methylpyridine | HCID 44754752 | — |
| Reactant | HCID 86660965 | HCID 86660965 | — |
| Product | 3-(3-Bromo-phenyl)-1-(2-fluoro-6-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one | HCID 66666197 | — |
Reaction Steps
In analogy to example 74, step 5, from 3-(3-bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide (example 98, step 4) and 2-fluoro-4-iodo-6-picoline (CAS RN: [884494-45-5]) was prepared the title compound as colorless oil, MS (ESI+): m/z=412.1 ([M+H]+, 1Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-e616a5cf24eb4573b87d2e24d899d893 |
| Source note | uspto-grants-2014_07 |