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2-Fluoro-4-iodo-5-methylpyridine → 3-(4-Bromo-phenyl)-1-(2-fluoro-5-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Fluoro-4-iodo-5-methylpyridine | HCID 10060052 | — |
| 反応物 | 3-(4-Bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide | HCID 86660949 | — |
| 生成物 | 3-(4-Bromo-phenyl)-1-(2-fluoro-5-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one | HCID 67015504 | — |
反応手順
In analogy to example 74, step 5, from 3-(4-bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide (example 74, step 4) and 2-fluoro-4-iodo-5-picoline (CAS RN: [153034-94-7]) was prepared the title compound as a light yellow oil, MS (ESI−): m/z=410.0558 ([M−H]−, 1Br).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08765730B2 |
| 出典データセット | uspto-grants-2014_07 |
| ORD ID | ord-9d7296b118244a32a8e240bc53215f83 |
| 出典メモ | uspto-grants-2014_07 |