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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617571Generated: October 25, 2026

6-Bromoquinoline → 3-(4-Bromo-phenyl)-1-quinolin-6-yl-3-o-tolyl-propan-1-one

https://huagongshe.com/reaction/1617571

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
Reactant3-(4-Bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamideHCID 86660949—
Product3-(4-Bromo-phenyl)-1-quinolin-6-yl-3-o-tolyl-propan-1-oneHCID 67015580—

Reaction Steps

In analogy to example 74, step 5, from 3-(4-bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide (example 74, step 4) and 6-bromoquinoline (CAS RN: [5332-25-2]) was prepared the title compound as a yellow oil, MS (ESI+): m/z=430.0791 ([M+H]+, 1Br).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-98b8198722124f7a949005730451f6a6
Source noteuspto-grants-2014_07