HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-bromo-2-(trifluoromethyl)- → 3-(4-Bromo-phenyl)-2-cyano-3-(2-trifluoromethyl-phenyl)-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-bromo-2-(trifluoromethyl)- | HCID 9806 | — |
| Reactant | Ethyl 3-(4-bromophenyl)-2-cyanoacrylate | HCID 5378084 | — |
| Product | 3-(4-Bromo-phenyl)-2-cyano-3-(2-trifluoromethyl-phenyl)-propionic acid ethyl ester | HCID 66666338 | — |
Reaction Steps
In analogy to example 74, step 2, from (E)-3-(4-bromo-phenyl)-2-cyano-acrylic acid ethyl ester and 2-bromobenzotrifluoride (CAS RN: [392-83-6]) was prepared the title compound as a brown oil, MS (ESI−): m/z=424.0 ([M−H]−, 1Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-c099356cf98c4b21ae54b9dd657773a6 |
| Source note | uspto-grants-2014_07 |