Boron tribromide → HCID 67015666, compound

HRID 1617615Notes

Reaction equation

HRID 1617615 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[CH3:28])[CH2:9][C:10]([C:12]2[CH:17]=[C:16]([CH3:18])[C:15]([O:19]C)=[C:14]([CH3:21])[CH:13]=2)=[O:11])=[CH:4][CH:3]=1.B(Br)(Br)Br>ClCCl>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[CH3:28])[CH2:9][C:10]([C:12]2[CH:13]=[C:14]([CH3:21])[C:15]([OH:19])=[C:16]([CH3:18])[CH:17]=2)=[O:11])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 67015706HCID 67015706, compound

Product 1

HCID 67015666HCID 67015666, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In analogy to example 151, step 2, 3-(4-bromo-phenyl)-1-(4-methoxy-3,5-dimethyl-phenyl)-3-o-tolyl-propan-1-one was treated with BBr3 in dichloromethane to give the title compound as a light yellow solid, MS (ESI+): m/z=420.9 [M−H]−.

Sources & evidence

ORD record
ord-20b587c6becd42b99764b6e91020e181
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

Loading…