1,1'-Carbonyldiimidazole → HCID 45867410, compound

HRID 1617628Notes

Reaction equation

HRID 1617628 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][N:4]=1.Cl.[CH3:13][NH:14][O:15][CH3:16].C(N1C=CN=C1)(N1C=CN=C1)=O>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([N:14]([O:15][CH3:16])[CH3:13])=[O:9])=[CH:5][N:4]=1

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 81138Methanamine, N-methoxy-, hydrochloride (1:1)HCID 5924996-Methoxynicotinic acid

Product 1

HCID 45867410HCID 45867410, compound

Procedure

In analogy to example 158, step 3, 6-methoxynicotinic acid was reacted with N,O-dimethylhydroxylamine hydrochloride and 1,1′-carbonyldiimidazole to give the title compound as a colorless oil, MS (ESI+): m/z=197.3 [M+H]+.

Sources & evidence

ORD record
ord-3673084e177e437ca1749431513d40f7
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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