Hydroxyamine hydrochloride → HCID 58043612, compound

Participants

Reaction Steps

In analogy to example 151, step 3, 5-[3-(4-bromo-phenyl)-7,7,7-trifluoro-heptanoyl]-1-methyl-1H-pyridin-2-one was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing 14% of the corresponding Z isomer as a colorless solid, MS (ESI+): m/z=445.3 [M+H]+.

Provenance & Evidence