Hydroxyamine hydrochloride → HCID 87237054, compound

Participants

Reaction Steps

In analogy to example 151, step 3, N-(2-acetylamino-ethyl)-4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzamide was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing less than 10% of the corresponding Z isomer as a colorless solid, MS (ESI+): m/z=475.2 [M+H]+.

Provenance & Evidence