Hydrochloric Acid → HCID 67015705, compound

HRID 1617779Notes

Reaction equation

HRID 1617779 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([C:20]1[CH:21]=[N:22][C:23]([O:26]C)=[CH:24][CH:25]=1)[CH2:9][C:10]([C:12]1[CH:13]=[N:14][C:15]([O:18]C)=[CH:16][CH:17]=1)=[O:11].Cl>O1CCOCC1>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([C:20]1[CH:25]=[CH:24][C:23](=[O:26])[NH:22][CH:21]=1)[CH2:9][C:10]([C:12]1[CH:17]=[CH:16][C:15](=[O:18])[NH:14][CH:13]=1)=[O:11]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 66668930HCID 66668930, compound

Product 1

HCID 67015705HCID 67015705, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

In analogy to example 162, step 2, 3-(2-chloro-phenyl)-1,3-bis-(6-methoxy-pyridin-3-yl)-propan-1-one was reacted with concentrated aqueous HCl in 1,4-dioxane to give the title compound as an off-white solid, MS (ESI+): m/z=355.1 [M+H]+.

Sources & evidence

ORD record
ord-4a4fa1919b2e4c7790061558741140a8
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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