Methyl iodide → HCID 67015630, compound

HRID 1617780Notes

Reaction equation

HRID 1617780 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([C:19]1[CH:20]=[CH:21][C:22](=O)[NH:23][CH:24]=1)[CH2:9][C:10]([C:12]1[CH:13]=[CH:14][C:15](=[O:18])[NH:16][CH:17]=1)=[O:11].I[CH3:27].[C:28](=[O:31])([O-])[O-].[K+].[K+]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([C:19]1[CH:20]=[CH:21][C:28](=[O:31])[N:23]([CH3:22])[CH:24]=1)[CH2:9][C:10]([C:12]1[CH:13]=[CH:14][C:15](=[O:18])[N:16]([CH3:27])[CH:17]=1)=[O:11]

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 67015705HCID 67015705, compound

Product 1

HCID 67015630HCID 67015630, compound

Procedure

In analogy to example 161, step 1, 5,5′-[1-(2-chlorophenyl)-3-oxopropane-1,3-diyl]dipyridin-2(1H)-one was reacted with iodomethane in the presence of potassium carbonate to give the title compound as a colorless solid, MS (ESI+): m/z=383.1 [M+H]+.

Sources & evidence

ORD record
ord-ea168ae255854315b8464edb0e6574cf
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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