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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617805Generated: November 3, 2026

Hydroxyamine hydrochloride → HCID 136166976, compound

https://huagongshe.com/reaction/1617805

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 66666620HCID 66666620—
ProductHCID 136166976HCID 136166976—

Reaction Steps

In analogy to example 132, step 6, from 1-{4-[(R)-3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-phenyl}-azetidine-3-carboxylic acid (example 279, step 1) and hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate was prepared the title compound as a yellow foam, MS (ESI+): m/z=466.2 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-9083d78d30fe48788219fb9a8e54530b
Source noteuspto-grants-2014_07