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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617812Generated: October 31, 2026

Hydroxyamine hydrochloride → HCID 136166865, compound

https://huagongshe.com/reaction/1617812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 66666451HCID 66666451—
ProductHCID 136166865HCID 136166865—

Reaction Steps

In analogy to example 132, step 6, from 1-{4-[(S)-1-(4-chloro-2-methyl-phenyl)-3-(2-methyl-pyridin-4-yl)-3-oxo-propyl]-phenyl}-piperidine-4-carboxylic acid and hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate was prepared the title compound as a light yellow foam, MS (ESI−): m/z=490.3 ([M−H]−).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-12cea1d9782443a893a62e465c4abf56
Source noteuspto-grants-2014_07